In brief
On 3 November, the UK Health Security Agency announced a new study to evaluate human exposure to per‑and polyfluoroalkyl substances, using data from the Health Survey for England. Early evidence hints at limited health impacts but suggests links to raised cholesterol and lower birth weight. The agency will collaborate internationally and does not recommend routine PFAS testing at present.
In London on Nov. 3, the UK Health Security Agency (UKHSA) announced a major study to assess people’s exposure to so‑called "forever chemicals"—per‑ and polyfluoroalkyl substances (PFAS)—alongside heavy metals such as lead and arsenic, and to investigate their possible health effects.
Scope of the Study
The study will analyze blood and urine samples collected through the existing Health Survey for England. By measuring pollutant levels in the population, UKHSA aims to understand the prevalence of PFAS, lead and arsenic exposure and to identify any potential risk factors linked to health outcomes.
Initial findings from the analysis are expected in 2027. The agency is working with international partners to monitor emerging evidence and assess possible health risks, noting that there is currently no recommendation for routine PFAS blood testing due to insufficient evidence about medical action for specific results.
Early Findings and Health Implications
Dr Edward Wynne‑Evans, UKHSA’s director of radiation, chemicals, climate and environmental hazards, said early evidence suggests that any health effects from PFAS are likely to be limited.
"The evidence available to date suggests that any health effects are likely to be limited," he said, adding that the strongest evidence currently points to possible associations with raised cholesterol and lower birth weight.
He emphasized that further research is needed to clarify these findings and determine their significance. While the preliminary data indicate limited impact, the agency acknowledges the concerns raised by wider scientific communities about the persistence of PFAS in the environment and their potential to affect human health over the long term.
Heavy metals such as lead and arsenic will be examined concurrently to provide a comprehensive assessment of chemical exposure. By employing a large, nationally representative sample, UKHSA hopes to generate robust data that can inform future public health policies and regulatory decisions.
As the study progresses, UKHSA will maintain close collaboration with international bodies, ensuring that emerging evidence is integrated and that the UK aligns with global monitoring standards.
At this stage, the agency has not advised citizens to undergo routine PFAS testing, citing gaps in knowledge about how specific test results should translate into medical or public‑health action.
Analysts say the findings will be crucial for understanding the long‑term health implications of chemical exposure and could guide future legislative efforts to limit PFAS use.