More than 35 people have been killed in Israeli strikes and gunfire since the early hours of Saturday morning, hospital sources in Gaza say.
A strike on a house in central Gaza left at least 11 people dead - more than half of them women and children - according to officials at al-Ahli Arab hospital in Gaza City.
Health workers said nine members of the same family were among those killed in an Israeli strike on the Nuseirat refugee camp, and at least six people are reported to have been killed while seeking aid in central and southern Gaza.
This comes a day after Israeli PM Benjamin Netanyahu told the United Nations that Israel must finish the job against Hamas.
The Israeli air force claims it has hit approximately 120 targets across the territory since Friday, including buildings linked to terrorist groups.
Israel’s military campaign is now primarily concentrated in Gaza City, which is viewed as the last stronghold of Hamas, following their lethal attack on southern Israel earlier this month.
Many civilians have been caught in the crossfire, as described by one resident: They tell us go there, then come back here... People are in the streets, in the south scattered everywhere. Where should we go? The humanitarian situation continues to deteriorate, with health services nearing collapse amidst an escalating famine crisis.
Despite mounting international pressure for a ceasefire and recognition of Palestinian statehood at the UN, Israel insists on maintaining pressure on Hamas. Netanyahu's assertive speech at the UN General Assembly faced walkouts from many delegations, underscoring global discontent over the ongoing conflict.
As hostilities persist, U.S. diplomatic efforts are concurrently underway, seeking to establish a new peace framework that may include a temporary alleviation of conflict. However, historical rigidity in negotiations underscores the challenges ahead.