A mass shooting at a crowded bar in the southern US state of South Carolina has left four people dead and at least 20 injured, officials reported.

Hundreds were gathered at the popular Willie's Bar and Grill on St Helena Island during the early hours of Sunday morning when gunfire erupted, prompting victims and attendees to flee to nearby businesses for safety, according to the Beaufort County Sheriff's Office.

Four individuals were pronounced dead at the scene, while at least 20 others sustained injuries, with four in critical condition reported to local hospitals. The situation remains under investigation, with authorities searching for possible suspects.

Upon arrival, police and emergency responders discovered multiple individuals suffering from gunshot wounds. Despite the chaotic scene, details are scarce regarding whether the incident was random or targeted, as the sheriff's office has declined to provide further comments.

Willie's Bar and Grill is known for its Gullah-inspired cuisine and is dedicated to sharing the spirit of the Gullah Geechee culture. This cultural group consists of descendants of enslaved Africans who were brought to the southeastern US coast, including South Carolina.

In a show of solidarity and support, South Carolina Republican Representative Nancy Mace expressed her sorrow over the shooting, stating on X, COMPLETELY HEARTBROKEN to learn about the devastating shooting in Beaufort County. Our prayers are with the victims, their families, and everyone impacted by this horrific act of violence.

Willie's Bar and Grill has yet to respond to inquiries regarding the incident.