Mabuza's rise was particularly notable as he played a pivotal role in ensuring Cyril Ramaphosa's ascent to the presidency. Initially supporting Ramaphosa's rival during the African National Congress's 2017 election conference, Mabuza ultimately shifted his allegiance, helping Ramaphosa secure a crucial victory. This shift was credited by some as a means to remove scandal-ridden former president Jacob Zuma's influence over the party and the country.

Despite his momentum as deputy president after Zuma's resignation in 2018, Mabuza's tenure was overshadowed by ongoing scrutiny over corruption. Political analysts note that Mabuza was a skilled political tactician, adept at navigating the complex landscape of South African politics. His legacy remains a mix of impactful leadership and a shadow of controversy, reflecting the challenges of governance in contemporary South Africa.